MRFF 2023 National Critical Research Infrastructure Grant Opportunity

This program provides funding to establish and extend infrastructure of critical importance, that will be used to conduct world-class health and medical research in areas of unmet medical need.
Closes in 122 days

Closing date: Monday 31 July 2023 5:00pm AEST Mon 31 Jul 2023 5:00pm AEST

What do you get?

Grants to fund research infrastructure projects, up to $3 million in Streams 1 and 2, up to $7 million in Stream 3 and up to $4 million in Stream 4.

Who is this for?

An eligible organisation who can support innovative medical research projects to improve health benefits for Australians.


The 2023 National Critical Research Infrastructure initiative invests in research infrastructure to ensure Australian researchers find innovative solutions to complex health problems in areas of unmet medical need. This grant opportunity has four streams:

Stream 1 – Innovation enablers

Addresses an area of unmet medical need by promoting the development and implementation of new research methodologies or applications including omics’-led approaches and enhanced infrastructure linkage strategies.

Stream 2 – Digitisation of health care

Translates or implements innovative artificial intelligence technologies into health applications that:

  • benefit multiple health disciplines/areas
  • involve consumers in the research journey to ensure the research is applicable to the needs of the Australian community; and
  • increase artificial intelligence workforce capacity and capability, particularly in relation to health, through cross-sector and interdisciplinary collaboration.

Stream 3 – Co-investment partnerships

Utilising co-investment (cash only) with the research sector, state and/or territory governments, and industry, in significant critical research infrastructure (e.g. facilities, personnel and equipment):

  • to support development of research capacity, capability and/or effectiveness in an area of unmet medical need, or
  • to enable Australian research using new platforms, systems and services in an area of unmet medical need.

Stream 4 – mRNA technology enablers

Leverage and enhance emerging mRNA technologies, platforms, and/or equipment to accelerate development of mRNA-based vaccines and therapeutics in an area of unmet medical need.

An application may only be submitted to one of the above four Streams only. An organisation may submit more than one application as long as it is unique - an applicant cannot submit the same project twice. Applicants must specify the Stream to which they are applying in their application.

The intended outcome of the research funded is to improve the health and wellbeing of Australians by enhancing Australia’s research infrastructure.

Check if you can apply

You can apply if you meet the eligibility criteria. The eligibility criteria are a set of rules that describe who we can consider for this grant. You can apply if you:

  • are an eligible entity
  • have an eligible project
  • have eligible expenditure
  • are applying under Stream 3 as a member of a consortia that:
    • includes at least one academic organisation and at least one other organisation which may be industry or state/territory government
    • contributes at least 34% of project costs in cash.

The rules are in the grant opportunity guidelines.

You can apply if you:

  • have an Australian business number (ABN)
  • are incorporated in Australia

and in accordance with s24 of the Medical Research Future Fund Act 2015, be one of the following entities:

  • a medical research institute
  • a university
  • a corporate Commonwealth entity
  • a corporation (including businesses and not for profits).

You can’t apply if you are:

  • an organisation, or your project partner is an organisation, included on the National Redress Scheme’s list of Institutions that have not joined or signified their intent to join the Scheme
  • an employer of 100 or more employees that has not complied with the Workplace Gender Equality Act (2012)
  • an individual
  • partnership
  • unincorporated association
  • trust (however, an incorporated trustee may apply on behalf of a trust)
  • a non-corporate Commonwealth entity
  • any organisation not listed in the eligible entity list.

Partner with other organisations

Joint applications are encouraged.

You can partner with one or more other organisations but you must decide who the lead organisation is.

Stream 3 applications must be from a consortia (including the applicant):

  • of at least one academic organisation and at least one other organisation which may be industry or state/territory government
  • with combined cash contributions of at least 34% of the total eligible project costs.

The lead organisation must fill out the application form.

If we give your group the grant, the lead organisation:

  • signs the grant agreement
  • receives grant payments
  • is responsible for making sure your group follows all requirements in the grant agreement, including all reporting requirements.

We can only accept applications that provide:

  • evidence from your board (or chief executive officer or equivalent if there is no board) that the project is supported, that you can complete the project and meet any costs not covered by grant funding
  • letters of support from each project partner/consortia partner
  • a list of up to 15 Chief Investigators using the template on (max 15 CIs and none listed on more than one application submitted per stream to this grant opportunity)
  • a detailed project plan (max 12 pages)
  • a detailed and itemised project budget
  • a one-page statement of how your project will contribute to the Measures of Success for the MRFF
  • a detailed risk management plan (max 2 pages)
  • details of IP arrangements

How to apply

Check if you’re ready to apply for a grant

Finding a suitable grant opportunity is just the start of the process to get funding. The application process can take time and effort. Understanding the entire process will help you be grant ready and may improve your chances of getting funding.

Use our checklist to find out what it takes to apply for a grant.

When you're ready to apply

Apply using our online portal:

  1. Create or log into your portal account.
  2. Follow the instructions to complete your application.
  3. Submit your application before the close date.

Make sure you include enough detail and supporting evidence in your application to help us decide whether to award you the grant.

Don’t submit the application until it’s complete. You can’t correct a mistake.

We know many businesses have concerns about the impact of COVID-19 on grant applications and grant management. When applying for a grant, consider timeframes and constraints that may impact grant activities due to COVID-19.

If COVID-19 has impacted your ability to meet the obligations of your grant agreement, to discuss your circumstances and how we can assist you, you should contact:

You can find further COVID-19 government financial assistance and support for Australian businesses on our coronavirus information and support for business page.

First we check that you meet the eligibility criteria. Eligible applications are then assessed against the assessment criteria by an independent committee of experts.

The amount of detail and supporting evidence you provide should be relative to the project size, complexity and grant amount requested. You should define, quantify and provide evidence to support your answers. The sample application form displays character limits.

The program delegate will make the final decision taking into consideration the recommendations from the independent committee of experts.

This grant opportunity has 4 streams with the following assessment criteria:

  • Assessment criterion 1: Project impact (40% weighting)
  • Assessment criterion 2: Project methodology (30% weighting)
  • Assessment criterion 3: Capacity, capability and resources to deliver the project (30% weighting)
  • Assessment criterion 4: Overall Value and Risk of the Project (non-weighted)

Scoring information for all assessment criteria can be found at Appendix C and Appendix D of the grant opportunity guidelines.

Apply now

Apply for the MRFF 2023 National Critical Research Infrastructure grant opportunity now

Before you apply, make sure you:

  • read and understand the grant opportunity guidelines
  • read the sample application form and grant agreement.
Apply now

Sample applications

The best way to understand what information you need to provide is to start an application. We have also provided a version to download at the bottom of this page.

Technical help

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Key documents

Grant opportunity guidelines

pdf · 0.50 MB docx · 1.90 MB

Sample application form

pdf · 0.41 MB docx · 0.23 MB

Sample grant agreement

pdf · 0.31 MB docx · 1.18 MB

Board/CEO letter template

pdf · 0.01 MB docx · 0.03 MB

Progress Report template

pdf · 0.24 MB docx · 1.14 MB

End of project report template

pdf · 0.28 MB docx · 1.15 MB

Independent audit report template

pdf · 0.35 MB docx · 0.05 MB

Chief Investigator template

xlsx · 0.21 MB